Fleeing from a dog catcher, the Two Curious Puppies run to an old remote house where, upon entering, they are continually subject to the antics of a mischievous magician's rabbit and surprise by the house's magical items.
Mr. Motto (Porky) is called back from vacation to catch the invisible man.
Porky works at the Snappy Rubber Company. His dog, Flat Foot Flookey, is determined to follow him into the plant, despite the rules. And Flookey's clumsiness means he's not exactly going to be able to sneak in like when he falls into a vat of rubberizing solution, and molds his face into a number of then-popular movie stars, or makes Porky's boss (a walrus) drop a stack of tires.
Porky and his friend Dizzy Duck go fishing, but their trip is cut short by a thunderstorm. They take refuge in an old building that appears haunted, though the biggest hazards are an old bearskin that lands on a swivel chair, a dog that gets tangled up in chains and a diving helmet, and their own clumsiness generally.
The Two Curious Puppies visit a model home with a panoply of modern inventions, including an annoying robot that sweeps up anything that touches the floor.
The Lone Stranger is sleeping when his faithful, if overly caricatured, Indian scout sees stagecoach driver Porky being robbed by a bad guy. The scout summons the Lone Stranger, who rides to the rescue. The bad guy goes after him (and, briefly, the narrator). But just in the nick of time, the Lone Stranger recovers and conquers the bad guy. Meanwhile, Silver and the villain's horse have been having their own close encounter, and Silver returns with several little colts.
The mice are on the loose after hours in a doctor's office, playing with the various pieces of medical apparatus. Susie Mouse is caged for research until her lover Johnnie frees her. A mouse orchestra plays a swinging wedding song. But throughout, a cat is stalking...
Egghead decides his road to riches is through a boxing correspondence course. When he graduates, he takes on champion Biff Stew. Biff pummels him mercilessly (the correspondence course record continues to coach him during the match), but by accident, he knocks Biff out until we see it was all in Egghead's head, after being knocked out by the practice equipment.
A battleship, manned mainly by dogs (and Porky), and whose captain sounds rather like Yosemite Sam, sets sail. When the crew threatens to get to the mess hall before the captain, he orders them to halt (and they do, some in mid-air). The ship gets a radio message of a reward for capturing the pirate submarine. The crew sets out in planes to go looking, leaving Porky behind. Naturally, the sub comes after the ship, and defense is up to Porky. He manages to repel the boarding party and winches the sub onboard with a plunger.
After being thrown out of the operating room as Dr. Quack's assistant, Dr. Daffy Duck makes Porky Pig his own - unwilling - patient.
A little cat must take his sick father's place as night watchman, but is bullied by a tough mouse and his gang, leaving the rest of the mice free to eat all the food and stage a musical floor show.
