In one fell swoop, nine-year old David Van de Steen lost his mother, his father and his sister in an attack by the Brabant Killers in Aalst. His grandfather, Albert, has the well-nigh impossible task of giving David a new perspective on life, a future.
Tom has a nightmare of being pounded by a giant dog. Jerry lures Tom into a series of encounters with a miniature vicious bulldog.
Jerry uses a robot mouse to snatch a sample from a lunar cheese mine being mined by robots; Tom gives chase with a robot cat.
Tom watches and studies films of some of his earlier encounters with Jerry, much like game films; he runs them backwards and stops them so he can study them more closely, all the while scribbling notes. Jerry pulls up a box of popcorn and watches, too. Tom notices Jerry and chases him into his hole. Tom designs a better mousetrap, but Jerry alters the plans, so it doesn't work any better than it did the first time the footage was used, in Designs on Jerry (1955).
Tom and Jerry are taking a cruise when Tom decides to go surfing. He has problems with a shark and a rather tenacious starfish.
Secret agent Jerry-akin has to steal a giant refrigerator full of cheese, guarded by the evil Tom Thrush with a vast array of diabolical gadgets and traps. Of course, Jerry has a few tricks of his own.
Tom chases Jerry into a fish cannery; they get sealed into cans. Tom breaks out, but falls off a pier as the cans roll under him. A shark chases him out of the water; Tom drops an anchor on the shark. Meanwhile, Jerry has been hopping in his can; Tom opens it, and puts his finger in, which Jerry bites. Jerry tricks Tom into falling off the end of another pier, and right into the shark's path again. The shark manages to get Tom into a very precarious position, barely holding the jaws apart. Jerry takes pity, and dumps a shaker full of pepper into the shark, which ends up on the processing line and stuffed into a huge can. Tom is unrepentant, so Jerry tricks him with a fake shark fin.
Jerry heads out to his night job: drummer for an all-mouse rock band in the basement of a high-rise. They are loud enough to wake up Tom, despite his attempts to block the noise. Tom's attempts keep running him afoul of a rather mean-tempered dog.
2565 AD. Tom and Jerry are once again manipulating robot versions of themselves in space. Tom experiments with invisibility, a giant electromagnet, and explosives, with results from bad to disastrous.
A supply satellite arrives at the space station where Tom (despite his high-tech gadgets) is having no better luck than usual at catching Jerry before he gets the cheese.
Tom is on the canals of Venice, singing opera. He ends up on a cruise ship, where another cat tricks him out of Jerry (who Tom has just caught), then mirrors his every move. Eventually the cats start chasing each other.
Jerry's mouse hole connects two homes, with Tom living in one residence, a neighboring cat in the other. Jerry decides the best survival plan is pitting the cats against each other, without their knowledge.